Julia Große, Charlotte Huppertz, Astrid Röh, Viola Oertel, Sara Andresen, Niklas Schade, Franziska Goerke-Arndt, Anna Kastinger, Nikola Schoofs, Philipp Arthur Thomann, Karsten Henkel, Berend Malchow, Jens Plag, Aleksandra Terziska, Ralf Brand, Frank Helmig, Alexander Schorb, Dirk Wedekind, Maria Jockers-Scherübl, Frank Schneider, Moritz Bruno Petzold, Andreas Ströhle
- Evidence for the effectiveness of physical activity (PA) in the treatment of depression prevails for outpatients with mild and moderate symptom levels. For inpatient treatment of severe depression, evidence-based effectiveness exists only for structured and supervised group PA interventions. The Step Away from Depression (SAD) study investigated the effectiveness of an individual pedometer intervention (PI) combined with an activity diary added to inpatient treatment as usual (TAU). In this multicenter randomized controlled trial, 192 patients were randomized to TAU or TAU plus PI. The two primary outcomes at discharge were depression—blindly rated with the Montgomery–Åsberg Depression Rating Scale (MADRS)—and average number of daily steps measured by accelerometers. Secondary outcomes were self-rated depression and PA, anxiety, remission and response rates. Multivariate analysis of variance (MANOVA) revealed no significant difference between both groups for depression and daily steps.Evidence for the effectiveness of physical activity (PA) in the treatment of depression prevails for outpatients with mild and moderate symptom levels. For inpatient treatment of severe depression, evidence-based effectiveness exists only for structured and supervised group PA interventions. The Step Away from Depression (SAD) study investigated the effectiveness of an individual pedometer intervention (PI) combined with an activity diary added to inpatient treatment as usual (TAU). In this multicenter randomized controlled trial, 192 patients were randomized to TAU or TAU plus PI. The two primary outcomes at discharge were depression—blindly rated with the Montgomery–Åsberg Depression Rating Scale (MADRS)—and average number of daily steps measured by accelerometers. Secondary outcomes were self-rated depression and PA, anxiety, remission and response rates. Multivariate analysis of variance (MANOVA) revealed no significant difference between both groups for depression and daily steps. Mean MADRS scores at baseline were 29.5 (SD = 8.3) for PI + TAU and 28.8 (SD = 8.1) for TAU and 16.4 (SD = 10.3) and 17.2 (SD = 9.9) at discharge, respectively. Daily steps rose from 6285 (SD = 2321) for PI + TAU and 6182 (SD = 2290) for TAU to 7248 (SD = 2939) and 7325 (SD = 3357). No differences emerged between groups in secondary outcomes. For severely depressed inpatients, a PI without supervision or further psychological interventions is not effective. Monitoring, social reinforcement and motivational strategies should be incorporated in PA interventions for this population to reach effectiveness.…
MetadatenAuthor: | Julia Große, Charlotte Huppertz, Astrid RöhORCiDGND, Viola Oertel, Sara Andresen, Niklas Schade, Franziska Goerke-Arndt, Anna Kastinger, Nikola Schoofs, Philipp Arthur Thomann, Karsten Henkel, Berend Malchow, Jens Plag, Aleksandra Terziska, Ralf Brand, Frank Helmig, Alexander Schorb, Dirk Wedekind, Maria Jockers-Scherübl, Frank Schneider, Moritz Bruno Petzold, Andreas Ströhle |
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URN: | urn:nbn:de:bvb:384-opus4-1072285 |
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Frontdoor URL | https://opus.bibliothek.uni-augsburg.de/opus4/107228 |
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ISSN: | 0940-1334OPAC |
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ISSN: | 1433-8491OPAC |
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Parent Title (English): | European Archives of Psychiatry and Clinical Neuroscience |
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Publisher: | Springer Science and Business Media LLC |
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Type: | Article |
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Language: | English |
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Year of first Publication: | 2024 |
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Publishing Institution: | Universität Augsburg |
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Release Date: | 2023/08/25 |
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Tag: | Pharmacology (medical); Biological Psychiatry; Psychiatry and Mental health; General Medicine |
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Volume: | 274 |
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First Page: | 709 |
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Last Page: | 721 |
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DOI: | https://doi.org/10.1007/s00406-023-01646-2 |
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Institutes: | Medizinische Fakultät |
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| Medizinische Fakultät / Lehrstuhl für Psychiatrie und Psychotherapie |
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Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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Licence (German): | CC-BY 4.0: Creative Commons: Namensnennung (mit Print on Demand) |
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