TY - JOUR A1 - Linseisen, Jakob A1 - Renner, Britta A1 - Gedrich, Kurt A1 - Wirsam, Jan A1 - Holzapfel, Christina A1 - Lorkowski, Stefan A1 - Watzl, Bernhard A1 - Daniel, Hannelore A1 - Leitzmann, Michael T1 - Data in personalized nutrition: bridging biomedical, psycho-behavioral, and food environment approaches for population-wide impact T2 - Advances in Nutrition N2 - Personalized Nutrition (PN) represents an approach aimed at delivering tailored dietary recommendations, products or services to support both prevention and treatment of nutrition-related conditions and improve individual health using genetic, phenotypic, medical, nutritional, and other pertinent information. However, current approaches have yielded limited scientific success in improving diets or in mitigating diet-related conditions. In addition, PN currently caters to a specific subgroup of the population rather than having a widespread impact on diet and health at a population level. Addressing these challenges requires integrating traditional biomedical and dietary assessment methods with psycho-behavioral, and novel digital and diagnostic methods for comprehensive data collection, which holds considerable promise in alleviating present PN shortcomings. This comprehensive approach not only allows for deriving personalized goals (“what should be achieved”) but also customizing behavioral change processes (“how to bring about change”). We herein outline and discuss the concept of “Adaptive Personalized Nutrition Advice Systems” (APNASs), which blends data from three assessment domains: 1) biomedical/health phenotyping; 2) stable and dynamic behavioral signatures; and 3) food environment data. Personalized goals and behavior change processes are envisaged to no longer be based solely on static data but will adapt dynamically in-time and in-situ based on individual-specific data. To successfully integrate biomedical, behavioral and environmental data for personalized dietary guidance, advanced digital tools (e.g., sensors) and artificial intelligence (AI)-based methods will be essential. In conclusion, the integration of both established and novel static and dynamic assessment paradigms holds great potential for transitioning PN from its current focus on elite nutrition to a widely accessible tool that delivers meaningful health benefits to the general population. Y1 - 2025 UR - https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/118537 UR - https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-1185374 SN - 2161-8313 N1 - Published on behalf of the Working Group "Personalized Nutrition" of the German Nutrition Society. Please see publisher's website for further details. VL - 16 IS - 7 SP - 100377 PB - Elsevier BV CY - Amsterdam ER -