TY  - INPR
A1  - Hoppe, Ronald H. W.
A1  - Linsenmann, Christopher
A1  - Zeleke, Kidist
T1  - Numerical Simulation of Surface Acoustic Wave Actuated Enantiomer Separation by the Finite Element Immersed Boundary Method
N2  - Enantiomers are chiral objects such as chemical molecules that can be distinguished by their handedness. They typically occur as racemic compounds of left- and right-handed species which may have completely different properties. Therefore, in applications such as drug design in pharmacology, enantiomer separation is an important issue. Here, we present a new technology for enantiomer separation by surface acoustic wave generated vorticity patterns consisting of pairwise counter-rotating vortices in a carrier fluid. The enantiomers are injected onto the surface of the fluid between two counter-rotating vortices such that right-handed (left-handed) enantiomers get attracted by left-rotating (right-rotating) vortices. In particular, we are concerned with the numerical simulation of this separation process by an application of the finite element immersed boundary method which relies on the solution of a coupled system consisting of the incompressible Navier-Stokes equations and the equations of motion of the immersed enantiomers described with respect to an Eulerian and a Lagrangian coordinate system. For a model system of deformable, initially L-shaped enantiomers the results of the numerical simulations reveal a perfect separation.
T3  - Preprints des Instituts für Mathematik der Universität Augsburg - 2012-10 
KW  - enantiomer separation
KW  - fluid mechanics
KW  - Strömungsmechanik
KW  - surface acoustic waves
KW  - finite element immersed boundary method
KW  - Akustische Oberflächenwelle
KW  - Finite-Elemente-Methode
Y1  - 2012
UR  - https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/2064
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-20642
ER  -