- Oral e-Poster Presentations - Booth 1: Trends & Innovation A, September 26, 2023, 1:00 PM - 2:30 PM
Background: Antibiotic therapy of cranial infections is a resource-intensive process. On the background of the recommendation for longer-term antibiotic administration for cranial infections, we established an outpatient intravenous antibiotic administration in our hospital.
Methods: The aim of this study was to evaluate the usefulness of outpatient antibiotic therapy in cranial neurosurgery. For this purpose, we included all patients who received a peripherally inserted central catheter (PICC line) for intravenous antibiotic therapy for cranial infections between 01/20 and 9/22. We evaluated the available patient data with regard to the infectiological and neurosurgical issues. All patients received intravenous antibiotics for at least 6 weeks (inpatient and outpatient).
Results: In total, we were able to include 30 patients. The median age was 58.12 years (SD +/- 13.39 years).Oral e-Poster Presentations - Booth 1: Trends & Innovation A, September 26, 2023, 1:00 PM - 2:30 PM
Background: Antibiotic therapy of cranial infections is a resource-intensive process. On the background of the recommendation for longer-term antibiotic administration for cranial infections, we established an outpatient intravenous antibiotic administration in our hospital.
Methods: The aim of this study was to evaluate the usefulness of outpatient antibiotic therapy in cranial neurosurgery. For this purpose, we included all patients who received a peripherally inserted central catheter (PICC line) for intravenous antibiotic therapy for cranial infections between 01/20 and 9/22. We evaluated the available patient data with regard to the infectiological and neurosurgical issues. All patients received intravenous antibiotics for at least 6 weeks (inpatient and outpatient).
Results: In total, we were able to include 30 patients. The median age was 58.12 years (SD +/- 13.39 years). The proportion of female patients was 43%. The mean hospital stay was 18.4 days (SD +/- 4.97 days) for total inpatient treatment. Subsequent mean outpatient antibiotic therapy was admitted for 71.7 days (SD +/- 23.18 days). Outpatient mean IV therapy accounted for 53.88 days (SD +/- 18.56 days). The most common pathogens were Staphylococcus epidermis and cutibacteria. In 9%, microbiological samples were. In all patients, neither radiographic nor laboratory evidence of inflammation was found in the final control. During outpatient intravenous therapy, 12% of patients experienced a difficult patency of the PICC line due to the prolonged administration of antibiotics. This could be corrected radiologically in each case. In addition, one patient, independent of therapy, showed structural epilepsy after the abscess healing.
Conclusions: Outpatient IV antibiotic therapy via a PICC line catheter is a safe and feasible method for long-term antibiotic treatment of cranial infections.…
