The central oscillatory network of essential tremor

  • The responsible pathological mechanisms of essential tremor are not yet clear. In order to understand the mechanisms of the central network its sources need to be found. The cortical sources of both the basic and first “harmonic” frequency of essential tremor are addressed in this paper. The power and coherence were estimated using the multitaper method for EEG and EMG data from 6 essential tremor patients. The Dynamic Imaging of Coherent Sources (DICS) was used to find the coherent sources in the brain. Before hand this method was validated for the application of finding multiple sources for the same oscillation in the brain by using two model simulations which indicated the accuracy of the method. In all the essential tremor patients the corticomuscular coherence was also present in the basic and the first harmonic frequency of the tremor. The source for the basic frequency and the first harmonic frequency was in the region of primary sensory motor cortex, prefrontal and in theThe responsible pathological mechanisms of essential tremor are not yet clear. In order to understand the mechanisms of the central network its sources need to be found. The cortical sources of both the basic and first “harmonic” frequency of essential tremor are addressed in this paper. The power and coherence were estimated using the multitaper method for EEG and EMG data from 6 essential tremor patients. The Dynamic Imaging of Coherent Sources (DICS) was used to find the coherent sources in the brain. Before hand this method was validated for the application of finding multiple sources for the same oscillation in the brain by using two model simulations which indicated the accuracy of the method. In all the essential tremor patients the corticomuscular coherence was also present in the basic and the first harmonic frequency of the tremor. The source for the basic frequency and the first harmonic frequency was in the region of primary sensory motor cortex, prefrontal and in the diencephalon on the contralateral side for all the patients. Thus the generation of these two oscillations involves the same cortical areas and indicates the oscillation at double the tremor frequency is a harmonic of the basic tremor frequency.show moreshow less

Download full text files

  • 110372.pdfeng
    (322KB)

    Postprint. © 2010 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

Export metadata

Statistics

Number of document requests

Additional Services

Share in Twitter Search Google Scholar
Metadaten
Author:Muthuraman MuthuramanORCiDGND, U. Heute, Günther Deuschl, Jan Raethjen
URN:urn:nbn:de:bvb:384-opus4-1103727
Frontdoor URLhttps://opus.bibliothek.uni-augsburg.de/opus4/110372
ISBN:978-1-4244-4123-5OPAC
Parent Title (English):2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 31 August - 04 September 2010, Buenos Aires, Argentina
Publisher:IEEE
Place of publication:Piscataway, NJ
Editor:Ricardo Armentano, Donna Hudson, Emilio Sacristan
Type:Conference Proceeding
Language:English
Year of first Publication:2010
Publishing Institution:Universität Augsburg
Release Date:2023/12/21
First Page:154
Last Page:157
DOI:https://doi.org/10.1109/iembs.2010.5627211
Institutes:Fakultät für Angewandte Informatik
Fakultät für Angewandte Informatik / Institut für Informatik
Fakultät für Angewandte Informatik / Institut für Informatik / Professur für Informatik in der Medizintechnik
Dewey Decimal Classification:0 Informatik, Informationswissenschaft, allgemeine Werke / 00 Informatik, Wissen, Systeme / 004 Datenverarbeitung; Informatik
Licence (German):Deutsches Urheberrecht