Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer
- Pathogenic variants (PVs) in DNA repair–linked adult-onset cancer predisposition genes, including double heterozygosity, are increasingly identified in pediatric patients with cancer. Their role in childhood cancer, however, remains poorly understood. Integrating comprehensive tumor analysis is integral for understanding the contribution of such PVs in cancer development and personalized cancer care.
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| Author: | Michaela KuhlenGND, Thomas G. Hofmann, Monika M. GolasORCiDGND |
|---|---|
| Frontdoor URL | https://opus.bibliothek.uni-augsburg.de/opus4/112308 |
| ISSN: | 2405-8033OPAC |
| Parent Title (English): | Trends in Cancer |
| Publisher: | Elsevier BV |
| Type: | Article |
| Language: | English |
| Year of first Publication: | 2024 |
| Publishing Institution: | Universität Augsburg |
| Release Date: | 2024/04/05 |
| Tag: | Cancer Research; Oncology |
| DOI: | https://doi.org/10.1016/j.trecan.2024.02.011 |
| Institutes: | Medizinische Fakultät |
| Medizinische Fakultät / Universitätsklinikum | |
| Medizinische Fakultät / Lehrstuhl für Kinder- und Jugendmedizin | |
| Medizinische Fakultät / Lehrstuhl für Humangenetik | |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Latest Publications (not yet published in print): | Aktuelle Publikationen (noch nicht gedruckt erschienen) |
| Licence (German): |  CC-BY-NC 4.0: Creative Commons: Namensnennung - Nicht kommerziell (mit Print on Demand) |
