New perspectives: systems medicine in cardiovascular disease

  • Background Cardiovascular diseases (CVD) represent one of the most important causes of morbidity and mortality worldwide. Innovative approaches to increase the understanding of the underpinnings of CVD promise to enhance CVD risk assessment and might pave the way to tailored therapies. Within the last years, systems medicine has emerged as a novel tool to study the genetic, molecular and physiological interactions. Conclusion In this review, we provide an overview of the current molecular-experimental, epidemiological and bioinformatical tools applied in systems medicine in the cardiovascular field. We will discuss the status and challenges in implementing interdisciplinary systems medicine approaches in CVD.

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Metadaten
Author:Frank KramerORCiDGND, Steffen Just, Tanja Zeller
URN:urn:nbn:de:bvb:384-opus4-1140215
Frontdoor URLhttps://opus.bibliothek.uni-augsburg.de/opus4/114021
ISSN:1752-0509OPAC
Parent Title (English):BMC Systems Biology
Publisher:Springer Science and Business Media LLC
Type:Article
Language:English
Year of first Publication:2018
Publishing Institution:Universität Augsburg
Release Date:2024/07/15
Volume:12
Issue:1
First Page:57
DOI:https://doi.org/10.1186/s12918-018-0579-5
Institutes:Fakultät für Angewandte Informatik
Fakultät für Angewandte Informatik / Institut für Informatik
Fakultät für Angewandte Informatik / Institut für Informatik / Lehrstuhl für IT-Infrastrukturen für die Translationale Medizinische Forschung
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):CC-BY 4.0: Creative Commons: Namensnennung (mit Print on Demand)