- Objective: The utility of intraoperative radiotherapy (IORT) has been demonstrated in many and diverse surgical fields. However, data regarding the application in patients with brain metastases is scares.
Methods: A retrospective study of nonconsecutive patients following surgical resection and IORT of brain metastasis between January 2013 and October 2020 was performed. Surgical and Oncological outcome was evaluated.
Results: 42 patients were identified. 55% were Female. Median Age was 61 (range 39 – 83). Breast cancer and malignant melanoma were seen the most common pathologies and were found in 19% an 17% of cases, respectively. The laterality was distributed equal and 86% were located supratentorial. 14% of the metastasis were seen in eloquent regions. IORT delivered a mean of 20 Gy (range 13 – 20). Mean Follow up was 36 Months (range 1 -180). Local tumor control was seen in 88% of all cases. Surgical complications were seen in 7% of cases (2 wound healing disorder and oneObjective: The utility of intraoperative radiotherapy (IORT) has been demonstrated in many and diverse surgical fields. However, data regarding the application in patients with brain metastases is scares.
Methods: A retrospective study of nonconsecutive patients following surgical resection and IORT of brain metastasis between January 2013 and October 2020 was performed. Surgical and Oncological outcome was evaluated.
Results: 42 patients were identified. 55% were Female. Median Age was 61 (range 39 – 83). Breast cancer and malignant melanoma were seen the most common pathologies and were found in 19% an 17% of cases, respectively. The laterality was distributed equal and 86% were located supratentorial. 14% of the metastasis were seen in eloquent regions. IORT delivered a mean of 20 Gy (range 13 – 20). Mean Follow up was 36 Months (range 1 -180). Local tumor control was seen in 88% of all cases. Surgical complications were seen in 7% of cases (2 wound healing disorder and one case of postoperative hemorrhage).
Conclusions: IORT is a safe and effective method to achieve sustainable local tumor control for patients with brain metastases.…
