Open Access

Trang Dao-Siebel, Jakob Holstiege, Kathrin Graw, Christoph Müller, Andreas Matzarakis, Roxana Halbleib, Evelyn Lamy

• Methods: Data on climate indicators and hay fever incidence in children and adolescents in the period 2013 to 2021 were implemented within the free software environment for statistical computing R using generalized additive Gamma family models. Results: Our results from all “seasonal”, “non-seasonal”, and “single-factor” models could not support the associations between the hay fever incidence and the precipitation as well as the concentrations of PM10, NO2, and O3 in Freiburg. However, they indicated statistically significant associations with temperature, and wind speed at the 5% level. The hay fever incidence was highest, as the temperature was between 4–6°C, and 10–17°C, and the wind speed was between 2.0 and 2.1m/s. Conclusions: This knowledge could be of relevance for the choice of patient treatment procedure in Freiburg, as the symptoms of a cold or flu can easily be mistaken for an allergy, especially in the cold season.