Implementation of gene expression profiles in the HL7 FHIR standard
- Gene expression profiles can capture significant molecular differences paving the way toward precision medicine. However, clinical standards like FHIR only provide encoding of molecular sequence variations, even so, expression patterns are equally important for decision making. Here we provide an exemplary implementation of gene expression profiles of a microarray analysis using an adaption of the FHIR Genomics extension. Our results demonstrate how FHIR resources can be facilitated in bioinformatics-based decision support systems or used for the aggregation of molecular genetics data in multi-center clinical trials.
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| Author: | Florian AuerORCiDGND, Zhibek Abdykalykova, Dominik MüllerORCiDGND, Frank KramerORCiDGND |
|---|---|
| URN: | urn:nbn:de:bvb:384-opus4-961064 |
| Frontdoor URL | https://opus.bibliothek.uni-augsburg.de/opus4/96106 |
| ISBN: | 978-1-64368-284-6OPAC |
| ISSN: | 0926-9630OPAC |
| ISSN: | 1879-8365OPAC |
| Parent Title (English): | Challenges of trustable AI and added-value on health: proceedings of MIE 2022 |
| Publisher: | IOS Press |
| Place of publication: | Amsterdam |
| Editor: | Brigitte Séroussi, Patrick Weber, Ferdinand Dhombres, Cyril Grouin, Jan-David Liebe, Sylvia Pelayo, Andrea Pinna, Bastien Rance, Lucia Sacchi, Adrien Ugon, Arriel Benis, Parisis Gallos |
| Type: | Conference Proceeding |
| Language: | English |
| Year of first Publication: | 2022 |
| Publishing Institution: | Universität Augsburg |
| Release Date: | 2022/06/15 |
| First Page: | 417 |
| Last Page: | 418 |
| Series: | Studies in Health Technology and Informatics ; 294 |
| DOI: | https://doi.org/10.3233/shti220490 |
| Institutes: | Fakultät für Angewandte Informatik |
| Fakultät für Angewandte Informatik / Institut für Informatik | |
| Fakultät für Angewandte Informatik / Institut für Informatik / Lehrstuhl für IT-Infrastrukturen für die Translationale Medizinische Forschung | |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Licence (German): |  CC-BY-NC 4.0: Creative Commons: Namensnennung - Nicht kommerziell |
