Comparative federated analytics of blood transfused patients in five ICU databases: using Kullback-Leibler Divergence
- This study assesses feature distribution differences across five intensive care databases using Kullback-Leibler Divergence (KLD). Analyzing bidirectional KLD patterns between individual databases and the composite of others, stratifying by transfusion status. Results reveal heterogeneity: HiRID shows highest divergence in both directions, particularly among transfusion cases; UKA exhibits moderate overall divergence but pronounced differences in transfusion scenarios; MIMIC-IV shows minimal divergence, indicating closest alignment with group distributions. Notably, transfusion cases consistently display higher divergence than non-transfusion cases across all databases, highlighting institution-specific practices. These findings stress the importance of assessing data heterogeneity before implementing federated learning models to understand generalization capabilities.
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| Author: | Johanna Schwinn, Seyedmostafa SheikhalishahiORCiD, Matthaeus Morhart, Iñaki Soto-ReyORCiDGND, Mathias KasparORCiD, Ludwig Christian HinskeORCiDGND |
|---|---|
| URN: | urn:nbn:de:bvb:384-opus4-1256845 |
| Frontdoor URL | https://opus.bibliothek.uni-augsburg.de/opus4/125684 |
| ISBN: | 9781643686295OPAC |
| ISSN: | 0926-9630OPAC |
| ISSN: | 1879-8365OPAC |
| Parent Title (English): | Good evaluation - better digital health: proceedings of the EFMI Special Topic Conference 2025 |
| Publisher: | IOS Press |
| Place of publication: | Amsterdam |
| Editor: | Ursula H. Hübner, Jan-David Liebe, Arriel Benis, Nicole Egbert, Thomas Engelsma, Parisis Gallos, Daniel Flemming, Valentina Lichtner, Romaric Marcilly, Oscar Tamburis, Sidsel Villumsen |
| Type: | Conference Proceeding |
| Language: | English |
| Year of first Publication: | 2025 |
| Publishing Institution: | Universität Augsburg |
| Release Date: | 2025/10/10 |
| First Page: | 57 |
| Last Page: | 61 |
| Series: | Studies in Health Technology and Informatics ; 332 |
| DOI: | https://doi.org/10.3233/shti251495 |
| Institutes: | Medizinische Fakultät |
| Medizinische Fakultät / Universitätsklinikum | |
| Medizinische Fakultät / Lehrstuhl für Datenmanagement und Clinical Decision Support | |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Licence (German): |  CC-BY-NC 4.0: Creative Commons: Namensnennung - Nicht kommerziell (mit Print on Demand) |
