The cAMP pathway as therapeutic target in autoimmune and inflammatory diseases
- Nucleotide signaling molecules contribute to the regulation of cellular pathways. In the immune system, cyclic adenosine monophosphate (cAMP) is well established as a potent regulator of innate and adaptive immune cell functions. Therapeutic strategies to interrupt or enhance cAMP generation or effects have immunoregulatory potential in autoimmune and inflammatory disorders. Here, we provide an overview of the cyclic AMP axis and its role as a regulator of immune functions and discuss the clinical and translational relevance of interventions with these processes.
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| Author: | Verena K. RakerORCiDGND, Christian Becker, Kerstin Steinbrink |
|---|---|
| URN: | urn:nbn:de:bvb:384-opus4-1188335 |
| Frontdoor URL | https://opus.bibliothek.uni-augsburg.de/opus4/118833 |
| ISSN: | 1664-3224OPAC |
| Parent Title (English): | Frontiers in Immunology |
| Publisher: | Frontiers Media SA |
| Type: | Article |
| Language: | English |
| Year of first Publication: | 2016 |
| Publishing Institution: | Universität Augsburg |
| Release Date: | 2025/02/03 |
| Volume: | 7 |
| First Page: | 123 |
| DOI: | https://doi.org/10.3389/fimmu.2016.00123 |
| Institutes: | Medizinische Fakultät |
| Medizinische Fakultät / Universitätsklinikum | |
| Medizinische Fakultät / Professur für Experimentelle Allergologie und immunologische Intoleranz | |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Licence (German): |  CC-BY 4.0: Creative Commons: Namensnennung (mit Print on Demand) |
