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Update breast cancer 2024 part 1 - expert opinion on advanced breast cancer

  • Clinical evidence is interpreted based on clinical studies and personal experience which can lead to different interpretations of data. This makes the opinions issued by panels of experts such as the Advanced Breast Cancer Panel which convened in November 2023 for the seventh time (ABC7) particularly important. At the conference, current issues around advanced breast cancer were evaluated by an international team of experts. In 2023 the data on CDK4/6 inhibitors was so extensive that the answers to questions about the sequencing of therapy and the potential use of chemotherapy as an alternative therapy were relatively clear. Moreover, data on antibody drug conjugates which provides a good overview of their uses is available for all molecular subtypes. Some therapeutic settings, including patients with brain metastases or leptomeningeal disease, older patients, locally advanced breast cancer and visceral crises, continue to be particularly important and were discussed inClinical evidence is interpreted based on clinical studies and personal experience which can lead to different interpretations of data. This makes the opinions issued by panels of experts such as the Advanced Breast Cancer Panel which convened in November 2023 for the seventh time (ABC7) particularly important. At the conference, current issues around advanced breast cancer were evaluated by an international team of experts. In 2023 the data on CDK4/6 inhibitors was so extensive that the answers to questions about the sequencing of therapy and the potential use of chemotherapy as an alternative therapy were relatively clear. Moreover, data on antibody drug conjugates which provides a good overview of their uses is available for all molecular subtypes. Some therapeutic settings, including patients with brain metastases or leptomeningeal disease, older patients, locally advanced breast cancer and visceral crises, continue to be particularly important and were discussed in structured sessions. The scientific context of some of the topics discussed at ABC7 is presented and assessed here.show moreshow less

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Metadaten
Author:Rachel Würstlein, Hans-Christian Kolberg, Andreas D. Hartkopf, Tanja N. Fehm, Manfred Welslau, Florian Schütz, Peter A. Fasching, Wolfgang Janni, Isabell Witzel, Christoph Thomssen, Annika Krückel, Erik Belleville, Diana Lüftner, Michael Untch, Marc Thill, Manuel Hörner, Hans Tesch, Nina DitschORCiDGND, Michael P. Lux, Bahriye Aktas, Maggie Banys-Paluchowski, Florin-Andrei Taran, Achim Wöckel, Nadia Harbeck, Elmar Stickeler, Rupert Bartsch, Andreas Schneeweiss, Johannes Ettl, David Krug, Volkmar Müller
URN:urn:nbn:de:bvb:384-opus4-1168802
Frontdoor URLhttps://opus.bibliothek.uni-augsburg.de/opus4/116880
ISSN:0016-5751OPAC
ISSN:1438-8804OPAC
Parent Title (German):Geburtshilfe und Frauenheilkunde
Publisher:Georg Thieme
Type:Article
Language:English
Year of first Publication:2024
Publishing Institution:Universität Augsburg
Release Date:2024/11/21
Volume:84
Issue:6
First Page:529
Last Page:540
DOI:https://doi.org/10.1055/a-2300-5326
Institutes:Medizinische Fakultät
Medizinische Fakultät / Universitätsklinikum
Medizinische Fakultät / Professur für Operative und Konservative Senologie
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):CC-BY-NC-ND 4.0: Creative Commons: Namensnennung - Nicht kommerziell - Keine Bearbeitung (mit Print on Demand)