Characterization of crystalline forms of gaxilose, a diagnostic drug

  • Lactose intolerance is a pathology caused by lactase enzyme deficiency, usually produced in the intestinal cells provoking symptoms as abdominal pain, bloating, diarrhea, gas and nausea. Gaxilose, 4-O-β-D galactopyranosyl-d-xylose, is used as a diagnostic drug for a non-invasive method for hypolactasia diagnosis. To date, no definitive guide for identifying gaxilose and distinguishing between crystalline forms is available. Data have been collected from a number of different analytical techniques in order to provide a full characterization of the compound and a simple method to discriminate between two solid forms.

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Metadaten
Author:Federica Catti, Santos Hernández Gallego, Mónica BenitoORCiDGND, Elies Molins, Francisco Marquillas Olóndriz
URN:urn:nbn:de:bvb:384-opus4-1044491
Frontdoor URLhttps://opus.bibliothek.uni-augsburg.de/opus4/104449
ISSN:0008-6215OPAC
Parent Title (English):Carbohydrate Research
Publisher:Elsevier BV
Type:Article
Language:English
Year of first Publication:2021
Publishing Institution:Universität Augsburg
Release Date:2023/05/19
Tag:Organic Chemistry; Biochemistry; General Medicine; Analytical Chemistry
Volume:499
First Page:108232
DOI:https://doi.org/10.1016/j.carres.2021.108232
Institutes:Mathematisch-Naturwissenschaftlich-Technische Fakultät
Mathematisch-Naturwissenschaftlich-Technische Fakultät / Institut für Physik
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 53 Physik / 530 Physik
Licence (German):CC-BY-NC-ND 4.0: Creative Commons: Namensnennung - Nicht kommerziell - Keine Bearbeitung (mit Print on Demand)