Severe fetomaternal transfusion due to an unrecognized chorangioma in a dichorionic, diamniotic twin pregnancy

  • Objectives/hypothesis Severe fetomaternal transfusion due to an unrecognized chorangioma in a dichorionic, diamniotic twin pregnancy: case report and review of the literature. Study design Case report and retrospective narrative review. Methods Evaluation of 8 case reports. Case report A 32-year-old primigravida with dichorionic, diamniotic twin pregnancy developed growth discordance and hypertension. At 35 weeks, cesarean delivery revealed one viable twin and one severely anemic twin who died immediately postnatal. Fetomaternal transfusion was suspected, confirmed, and most likely caused by a 6 cm chorangioma. Conclusion Fetomaternal hemorrhage is a serious but underrecognized complication and can be caused of placental chorioangiomas, among other things. Although rare, it poses significant risks of fetal anemia and perinatal morbidity. Increased awareness and routine Doppler monitoring of at-risk fetuses may facilitate earlier diagnosis and timely intervention, potentiallyObjectives/hypothesis Severe fetomaternal transfusion due to an unrecognized chorangioma in a dichorionic, diamniotic twin pregnancy: case report and review of the literature. Study design Case report and retrospective narrative review. Methods Evaluation of 8 case reports. Case report A 32-year-old primigravida with dichorionic, diamniotic twin pregnancy developed growth discordance and hypertension. At 35 weeks, cesarean delivery revealed one viable twin and one severely anemic twin who died immediately postnatal. Fetomaternal transfusion was suspected, confirmed, and most likely caused by a 6 cm chorangioma. Conclusion Fetomaternal hemorrhage is a serious but underrecognized complication and can be caused of placental chorioangiomas, among other things. Although rare, it poses significant risks of fetal anemia and perinatal morbidity. Increased awareness and routine Doppler monitoring of at-risk fetuses may facilitate earlier diagnosis and timely intervention, potentially improving outcomes. Particularly in children with anemia, fetomaternal transfusion should always be considered and HbF material determined.show moreshow less

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Author:Jonas BubmannORCiD, Christian DanneckerORCiDGND, Manuela Franitza, Marina Seefried, Philipp Voisard, Udo JeschkeORCiDGND, Carl Mathis Wild, Fabian Garrido, Tina SchallerGND, Bernadette Eser
URN:urn:nbn:de:bvb:384-opus4-1273465
Frontdoor URLhttps://opus.bibliothek.uni-augsburg.de/opus4/127346
ISSN:1432-0711OPAC
Parent Title (English):Archives of Gynecology and Obstetrics
Publisher:Springer
Place of publication:Berlin
Type:Article
Language:English
Date of first Publication:2026/01/13
Publishing Institution:Universität Augsburg
Release Date:2026/01/23
Tag:Chorangioma; Fetal hemoglobin; Fetomaternal transfusion; Twin pregnancy
Volume:313
Issue:1
First Page:33
DOI:https://doi.org/10.1007/s00404-025-08249-3
Institutes:Medizinische Fakultät
Medizinische Fakultät / Universitätsklinikum
Medizinische Fakultät / Lehrstuhl für Allgemeine und Spezielle Pathologie
Medizinische Fakultät / Lehrstuhl für Frauenheilkunde
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):CC-BY 4.0: Creative Commons: Namensnennung