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  • Saad, Christian (19)
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Differential early diagnosis of benign versus malignant lung cancer using systematic pathway flux analysis of peripheral blood leukocytes (2022)
Li, Jian ; Li, Xiaoyu ; Li, Ming ; Qiu, Hong ; Saad, Christian ; Zhao, Bo ; Li, Fan ; Wu, Xiaowei ; Kuang, Dong ; Tang, Fengjuan ; Chen, Yaobing ; Shu, Hongge ; Zhang, Jing ; Wang, Qiuxia ; Huang, He ; Qi, Shankang ; Ye, Changkun ; Bryant, Amy ; Yuan, Xianglin ; Kurts, Christian ; Hu, Guangyuan ; Cheng, Weiting ; Mei, Qi
Ein Verfahren zur Struktur- und Verhaltensanalyse von UML-Modellen durch Attribute (2008)
Saad, Christian
Metamodellierung ist ein konzeptioneller Ansatz zur Formalisierung der Objektstruktur einer Anwendungsdomäne, der aktuell in der Softwaretechnik, aber auch in anderen Bereichen der Informatik, große Verbreitung findet. Im Gegensatz zu der, durch das Metamodell festgelegten, abstrakten Syntax lässt sich die Semantik eines Modells durch die momentan zur Verfügung stehenden Methodiken jedoch nur unzureichend beschreiben und überprüfen. Diese Arbeit entwickelt eine flexible und dynamische Technik zur statischen semantischen Analyse von Modellstrukturen, die auf einer Übertragung des auf kontextfreien Grammatiken definierten Attributierungskonzepts auf UML-Metamodelle beruht. Basierend auf diesem Verfahren wird zudem eine Variante des Datenflussanalyse-Algorithmus vorgestellt, die den Informationsfluss zwischen Modellelementen ermittelt, wodurch Erkenntnisse über das Verhalten auf Instanzebene gewonnen werden können. Der praktische Einsatz der beschriebenen Techniken wird anhand eines Anwendungsbeispiels und einer prototypischen Implementierung demonstriert.
Data-flow based Model Analysis: Approach, Implementation and Applications (2015)
Saad, Christian
During the past years, the modeling paradigm has become one of the predominant trends in the field of software engineering and has been embraced by industry and research alike. An important reason for this development is that models provide an intuitive yet concise way of formalizing the concepts of an application domain along with the relationships that exist between them. As a consequence, this technique now serves as an integral part of popular and widely used software design and development processes such as the Rational Unified Process (RUP) or the Model-driven Architecture (MDA) in order to characterize static and behavioral aspects of software systems. It also drives new approaches in other contexts, e.g. in testing (Model-based Testing), for the implementation and execution of business processes on the basis of high-level descriptions (Business Process Modeling) or through the provisioning of tools aimed at domain experts (Domain-specific Languages). However, the employment of abstraction (meta) layers to construct languages dates back a lot further than the comparatively new notion of modeling: The syntax of a programming language, usually given in the form of a context-free grammar, forms the basis for parsing language expressions into their respective structural representation. In many respects, the use of metamodels as means of defining the abstract syntax of languages therefore parallels formalisms and techniques common to the area of compiler construction. As the application fields of modeling expand to new areas where automated processing of the contained information becomes crucial to achieve the desired outcome, the demand for methods enabling advanced analyses of the modeled content increases. Since models themselves represent a layer of abstraction w.r.t. domain-specific runtime (or "real world") semantics, their elements can be subjected to a static analysis, i.e. an assessment of their static properties which are guaranteed to hold for all instances. Contemporary techniques for model analysis, such as the widely-used Object Constraint Language (OCL), suffer from many shortcomings with respect to their expressiveness. The conceptual similarities between the domains of modeling and compiler construction gave rise to the idea of applying the powerful and well-understood methods for static validation and optimization of formal language expressions - namely attribute grammars and data-flow analysis - to models. Hence, this thesis introduces the notion of flow-based static model analysis to enable the demand-driven, context-sensitive extraction and validation of a model's static properties and evaluates the applicability of this approach in the context of several case studies.
AutoAnalyze in Systems Biology (2019)
Saad, Christian ; Bauer, Bernhard ; Mansmann, Ulrich R. ; Li, Jian
Computational modeling of methionine cycle-based metabolism and DNA methylation and the implications for anti-cancer drug response prediction (2018)
Zhang, Mengying ; Saad, Christian ; Le, Lien ; Halfter, Kathrin ; Bauer, Bernhard ; Mansmann, Ulrich R. ; Li, Jian
Adaptive approach for impact analysis in enterprise architectures (2015)
Langermeier, Melanie ; Saad, Christian ; Bauer, Bernhard
A flow analysis approach for service-oriented architectures (2015)
Bauer, Bernhard ; Langermeier, Melanie ; Saad, Christian
A unified framework for enterprise architecture analysis (2014)
Langermeier, Melanie ; Saad, Christian ; Bauer, Bernhard
Parallelizing highly complex engine management systems (2017)
Kienberger, Julian ; Schmidhuber, Stefan ; Saad, Christian ; Kuntz, Stefan ; Bauer, Bernhard
Efficient parallelization of complex automotive systems (2016)
Kienberger, Julian ; Saad, Christian ; Kuntz, Stefan ; Bauer, Bernhard
Data-flow Based Model Analysis (2010)
Saad, Christian ; Bauer, Bernhard
Applying data-flow analysis to models a novel approach for model analysis (2010)
Saad, Christian ; Bauer, Bernhard
Analyzing dynamic models using a data-flow based approach (2010)
Saad, Christian ; Bauer, Bernhard
The Model Analysis Framework - An IDE for Static Model Analysis (2011)
Saad, Christian ; Bauer, Bernhard
Context-sensitive impact analysis for enterprise architecture management (2014)
Langermeier, Melanie ; Saad, Christian ; Bauer, Bernhard
Data-flow based model analysis and its applications (2013)
Saad, Christian ; Bauer, Bernhard
Geschäftsprozesse ausführen mit Eclipse JWT (2009)
Lautenbacher, Florian ; Saad, Christian ; Bauer, Bernhard
An attribute-based approach to the analysis of model characteristics (2009)
Saad, Christian ; Lautenbacher, Florian ; Bauer, Bernhard
Computational analysis of receptor tyrosine kinase inhibitors and cancer metabolism: implications for treatment and discovery of potential therapeutic signatures (2019)
Li, Jian ; Halfter, Kathrin ; Zhang, Mengying ; Saad, Christian ; Xu, Kai ; Bauer, Bernhard ; Huang, Yijiang ; Shi, Lei ; Mansmann, Ulrich R.
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